Learn how to use square breathing to help activate your parasympathetic nerve systems to help you calm down. To learn more, watch this video: • #071 Relax in 2 minutes with SQUARE B... Doctor Andrea Furlan demonstrates a relaxation technique called Square Breathing or Box Breathing. This breathing strategy is helpful for people who have chronic pain and anxiety. When the person feels that anxiety and fear are interfering with their life, they may take a 2-minute pause and do this relaxation. It activates the parasympathetic nervous system and counter-balances the sympathetic nervous system. The sympathetic nervous system is the stress response of fight or flight. The parasympathetic nervous system is the rest and digest system. During stressful situations, especially related to pain, it is helpful to stop and think, before the anxiety hormones and neurotransmitters of cortisol and noradrenaline are released.