ESMO 2020 Expert Video Report on CDK4 6i in the adjuvant treatment of breast cancer

Опубликовано: 30 Сентябрь 2020
на канале: European Society for Medical Oncology (ESMO)

1,356

Reporting from ESMO Virtual Congress 2020, Stephen Johnston features the results from the monarchE study on abemaciclib and from the PALLAS trial with palbociclib, as adjuvant treatment in patients with HR positive HER2 negative early Breast Cancer.
He elaborates possible reasons why outcome in these trials was very different, and insists on the importance of risk factors assessment, as well as management of adverse events to improve treatment compliance.

Abstracts:
LBA12 - PALLAS: PALbociclib CoLlaborative Adjuvant Study: A randomized phase III trial of palbociclib with adjuvant endocrine therapy versus adjuvant endocrine therapy alone for HR+/HER2- early breast cancer
LBA5_PR - Abemaciclib for the adjuvant treatment of high-risk early breast cancer
Simultaneous publication: https://ascopubs.org/doi/full/10.1200...

Produced by ESMO, https://oncologypro.esmo.org
This video was supported with educational grants from Bayer, Daiichi Sankyo and Novartis